All are invited to the Bradford Hill Seminar:

The SIREN study at five years: Tracking SARS-CoV-2 and respiratory infections in UK healthcare workers since 2020

Victoria Hall

Consultant Epidemiologist, Antimicrobial Resistance & Healthcare Associated Infections Division of the UK Health Security Agency (UK HSA)

Register to attend

Please note this will be a free hybrid seminar, with the option to attend in-person (Large Seminar Room, East Forvie Building, Forvie Site, Robinson Way, Cambridge CB2 0SR) or virtually (via Zoom).

No registration is required to attend in person.

Register in advance to attend this seminar online at:

• https://cam-ac-uk.zoom.us/meeting/register/CoavXVmNQtWN8j8TOFv-rg#/registration

Abstract

The SARS-CoV-2 Immunity and Reinfection Evaluation (SIREN) study is a prospective cohort study of hospital-based healthcare workers across the UK. It was established in 2020 as a pandemic response study, with over 44,000 healthcare workers recruited from 135 NHS trusts/health boards. The study initially investigated SARS-CoV-2 reinfections and the durability of immunity following infection, and subsequently COVID-19 vaccination. It has expanded its scope to evaluate Winter Pressures on the healthcare workforce, and questions related to immunity more broadly.

SIREN+ has been running since 2024. This has involved collecting data on symptoms and absence from time off work trends in around 5000 participants recruited from the original SIREN cohort. In addition to investigating Winter Pressures, SIREN+ provides an opportunity to address new research questions of public health importance that impact healthcare workers, including the emergence of multidrug resistant organisms and risk factors for healthcare associated infections.

More details on the study and publications from the study can be found here: https://www.gov.uk/guidance/siren-study

About Victoria Hall

Victoria Hall is a Consultant Epidemiologist in the Antimicrobial Resistance & Healthcare Associated Infections Division of the UK Health Security Agency and has been leading the SIREN study team since 2020.  She completed public health speciality training in the East of England and the UK Field Epidemiology Training Programme based in South East and London Regional Field Epidemiology Service.  She holds a part-time position at the Institute for Health Informatics, UCL working on research on infections and AMR in care homes with the VIVALDI study.

About the Bradford Hill seminars

The Bradford Hill seminar series is the principal series of The Cambridge Population Health Sciences Partnership, in collaboration with the PHG Foundation. This comprises the Departments of Public Health & Primary Care, MRC Biostatistics Unit and MRC Epidemiology Unit at the University of Cambridge, bringing together a multi-disciplinary partnership of academics and public health professionals. The Bradford Hill seminar programme of internationally recognised speakers covers topics of broad interest to our public health research community. It aims to transcend as well as connect the activities of our individual partners.

All are welcome at our Bradford Hill seminars.